Independent contribution of polygenic risk for schizophrenia and cannabis use in predicting psychotic-like experiences in young adulthood: testing gene × environment moderation and mediation

BACKGROUND: It has not yet been determined if the commonly reported cannabis–psychosis association is limited to individuals with pre-existing genetic risk for psychotic disorders. METHODS: We examined whether the relationship between polygenic risk score for schizophrenia (PRS-Sz) and psychotic-lik...

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Detalles Bibliográficos
Autores principales: Elkrief, Laurent, Lin, Bochao, Marchi, Mattia, Afzali, Mohammad H, Banaschewski, Tobias, Bokde, Arun L. W., Quinlan, Erin Burke, Desrivières, Sylvane, Flor, Herta, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Martinot, Marie-Laure Paillère, Nees, Frauke, Orfanos, Dimitri Papadopoulos, Paus, Tomáš, Poustka, Luise, Hohmann, Sarah, Fröhner, Juliane H., Smolka, Michael N., Walter, Henrik, Whelan, Robert, Schumann, Gunter, Luykx, Jurjen, Boks, Marco P., Conrod, Patricia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106286/
https://www.ncbi.nlm.nih.gov/pubmed/37310336
http://dx.doi.org/10.1017/S0033291721003378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106286/
https://www.ncbi.nlm.nih.gov/pubmed/37310336
http://dx.doi.org/10.1017/S0033291721003378

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