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Independent contribution of polygenic risk for schizophrenia and cannabis use in predicting psychotic-like experiences in young adulthood: testing gene × environment moderation and mediation
BACKGROUND: It has not yet been determined if the commonly reported cannabis–psychosis association is limited to individuals with pre-existing genetic risk for psychotic disorders. METHODS: We examined whether the relationship between polygenic risk score for schizophrenia (PRS-Sz) and psychotic-lik...
Autores principales: | Elkrief, Laurent, Lin, Bochao, Marchi, Mattia, Afzali, Mohammad H, Banaschewski, Tobias, Bokde, Arun L. W., Quinlan, Erin Burke, Desrivières, Sylvane, Flor, Herta, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Martinot, Marie-Laure Paillère, Nees, Frauke, Orfanos, Dimitri Papadopoulos, Paus, Tomáš, Poustka, Luise, Hohmann, Sarah, Fröhner, Juliane H., Smolka, Michael N., Walter, Henrik, Whelan, Robert, Schumann, Gunter, Luykx, Jurjen, Boks, Marco P., Conrod, Patricia J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106286/ https://www.ncbi.nlm.nih.gov/pubmed/37310336 http://dx.doi.org/10.1017/S0033291721003378 |
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