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Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis

PURPOSE: To investigate the effect of IV fluid resuscitation on endothelial glycocalyx (EG) shedding and activation of the vascular endothelium and inflammation. MATERIALS AND METHODS: A planned biomarker sub-study of the REFRESH trial in which emergency department (ED) patients) with suspected seps...

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Detalles Bibliográficos
Autores principales: Macdonald, Stephen, Bosio, Erika, Keijzers, Gerben, Burrows, Sally, Hibbs, Moira, O’Donoghue, Helen, Taylor, David, Mukherjee, Ashes, Kinnear, Frances, Smart, Lisa, Ascencio-Lane, Juan-Carlos, Litton, Edward, Fraser, John, Shapiro, Nathan I., Arendts, Glenn, Fatovich, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106534/
https://www.ncbi.nlm.nih.gov/pubmed/37062769
http://dx.doi.org/10.1186/s40635-023-00508-4