Loss of NLRP3 reduces oxidative stress and polarizes intratumor macrophages to attenuate immune attack on endometrial cancer

INTRODUCTION: The interaction between endometrial cancer (EMC) cells and intratumoral macrophages plays a significant role in the development of the disease. PYD domains-containing protein 3 (NLRP3) inflammasome formation triggers caspase-1/IL-1β signaling pathways and produces reactive oxygen speci...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolu, Xu, Yanli, Wang, Juan, Xue, Zhuowei, Qiu, Tian, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106583/
https://www.ncbi.nlm.nih.gov/pubmed/37077909
http://dx.doi.org/10.3389/fimmu.2023.1165602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106583/
https://www.ncbi.nlm.nih.gov/pubmed/37077909
http://dx.doi.org/10.3389/fimmu.2023.1165602

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