Resveratrol Improves Paclitaxel-Induced Cognitive Impairment in Mice by Activating SIRT1/PGC-1α Pathway to Regulate Neuronal State and Microglia Cell Polarization

OBJECTIVE: This study aimed to investigate the effect of resveratrol (Res) on paclitaxel (PTX)-induced cognitive impairment and elucidate the underlying molecular mechanisms. METHODS: Morris Water Maze (MWM) test was used to evaluate the mice’s spatial learning and memory abilities. Western blotting...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Tang, Miao, He, Tian-Yi, Zhao, Shuang, Li, Hui-Zhou, Li, Zhao, Guo, Yue-Xian, Wang, Xiu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106825/
https://www.ncbi.nlm.nih.gov/pubmed/37077409
http://dx.doi.org/10.2147/DDDT.S400936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106825/
https://www.ncbi.nlm.nih.gov/pubmed/37077409
http://dx.doi.org/10.2147/DDDT.S400936

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