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Resveratrol Improves Paclitaxel-Induced Cognitive Impairment in Mice by Activating SIRT1/PGC-1α Pathway to Regulate Neuronal State and Microglia Cell Polarization
OBJECTIVE: This study aimed to investigate the effect of resveratrol (Res) on paclitaxel (PTX)-induced cognitive impairment and elucidate the underlying molecular mechanisms. METHODS: Morris Water Maze (MWM) test was used to evaluate the mice’s spatial learning and memory abilities. Western blotting...
Autores principales: | Liu, Xin, Tang, Miao, He, Tian-Yi, Zhao, Shuang, Li, Hui-Zhou, Li, Zhao, Guo, Yue-Xian, Wang, Xiu-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106825/ https://www.ncbi.nlm.nih.gov/pubmed/37077409 http://dx.doi.org/10.2147/DDDT.S400936 |
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