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Spatially constrained gene regulation identifies key genetic contributions of preeclampsia, hypertension, and proteinuria

Preeclampsia (PE) is a relatively common but severe pregnancy disorder (with very limited effective treatments) characterized by hypertension (HTN) and usually proteinuria (PRO) or other organ damage. Genome-wide association studies (GWAS) of PE, HTN, and PRO have mostly identified risk loci single...

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Detalles Bibliográficos
Autores principales: Boom, Genevieve, O’Sullivan, Justin M, Schierding, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106839/
https://www.ncbi.nlm.nih.gov/pubmed/36738257
http://dx.doi.org/10.1093/biolre/ioad016