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Spatially constrained gene regulation identifies key genetic contributions of preeclampsia, hypertension, and proteinuria
Preeclampsia (PE) is a relatively common but severe pregnancy disorder (with very limited effective treatments) characterized by hypertension (HTN) and usually proteinuria (PRO) or other organ damage. Genome-wide association studies (GWAS) of PE, HTN, and PRO have mostly identified risk loci single...
Autores principales: | Boom, Genevieve, O’Sullivan, Justin M, Schierding, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106839/ https://www.ncbi.nlm.nih.gov/pubmed/36738257 http://dx.doi.org/10.1093/biolre/ioad016 |
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