Obesity partially potentiates dimethylbenz[a]anthracene-exposed ovotoxicity by altering the DNA damage repair response in mice

Obesity adversely affects reproduction, impairing oocyte quality, fecundity, conception, and implantation. The ovotoxicant, dimethylbenz[a]anthracene, is biotransformed into a genotoxic metabolite to which the ovary responds by activating the ataxia telangiectasia mutated DNA repair pathway. Basal o...

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Detalles Bibliográficos
Autores principales: Rishi, Jaspreet K, Timme, Kelsey, White, Hunter E, Kerns, Karl C, Keating, Aileen F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106840/
https://www.ncbi.nlm.nih.gov/pubmed/36702632
http://dx.doi.org/10.1093/biolre/ioac218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106840/
https://www.ncbi.nlm.nih.gov/pubmed/36702632
http://dx.doi.org/10.1093/biolre/ioac218

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