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Shear stress leads to the dysfunction of endothelial cells through the Cav-1-mediated KLF2/eNOS/ERK signaling pathway under physiological conditions

To investigate the mechanism of shear stress on endothelial cell dysfunction for providing a theoretical basis for the reduction of arteriovenous fistula dysfunction. The in vitro parallel plate flow chamber was used to form different forces and shear stress to mimic the hemodynamic changes in human...

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Detalles Bibliográficos
Autores principales: Wang, Lihua, Wang, Bingyue, Jia, Lan, Yu, Haibo, Wang, Zhe, Wei, Fang, Jiang, Aili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106974/
https://www.ncbi.nlm.nih.gov/pubmed/37077343
http://dx.doi.org/10.1515/biol-2022-0587