DASH/Dam1 complex mutants stabilize ploidy in histone‐humanized yeast by weakening kinetochore‐microtubule attachments

Forcing budding yeast to chromatinize their DNA with human histones manifests an abrupt fitness cost. We previously proposed chromosomal aneuploidy and missense mutations as two potential modes of adaptation to histone humanization. Here, we show that aneuploidy in histone‐humanized yeasts is specif...

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Detalles Bibliográficos
Autores principales: Haase, Max A B, Ólafsson, Guðjón, Flores, Rachel L, Boakye‐Ansah, Emmanuel, Zelter, Alex, Dickinson, Miles Sasha, Lazar‐Stefanita, Luciana, Truong, David M, Asbury, Charles L, Davis, Trisha N, Boeke, Jef D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106983/
https://www.ncbi.nlm.nih.gov/pubmed/36651597
http://dx.doi.org/10.15252/embj.2022112600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106983/
https://www.ncbi.nlm.nih.gov/pubmed/36651597
http://dx.doi.org/10.15252/embj.2022112600

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