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Batf stabilizes Th17 cell development via impaired Stat5 recruitment of Ets1‐Runx1 complexes

Although the activator protein‐1 (AP‐1) factor Batf is required for Th17 cell development, its mechanisms of action to underpin the Th17 program are incompletely understood. Here, we find that Batf ensures Th17 cell identity in part by restricting alternative gene programs through its actions to res...

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Detalles Bibliográficos
Autores principales: Pham, Duy, Silberger, Daniel J, Nguyen, Kim N, Gao, Min, Weaver, Casey T, Hatton, Robin D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106990/
https://www.ncbi.nlm.nih.gov/pubmed/36917143
http://dx.doi.org/10.15252/embj.2021109803