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Chloroacetamide‐Modified Nucleotide and RNA for Bioconjugations and Cross‐Linking with RNA‐Binding Proteins

Reactive RNA probes are useful for studying and identifying RNA‐binding proteins. To that end, we designed and synthesized chloroacetamide‐linked 7‐deaza‐ATP which was a good substrate for T7 RNA polymerase in in vitro transcription assay to synthesize reactive RNA probes bearing one or several reac...

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Detalles Bibliográficos
Autores principales: Brunderová, Mária, Krömer, Matouš, Vlková, Marta, Hocek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107093/
https://www.ncbi.nlm.nih.gov/pubmed/36533569
http://dx.doi.org/10.1002/anie.202213764