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Preparative‐Scale Biocatalytic Oxygenation of N‐Heterocycles with a Lyophilized Peroxygenase Catalyst

A lyophilized preparation of an unspecific peroxygenase variant from Agrocybe aegerita (rAaeUPO‐PaDa‐I‐H) is a highly effective catalyst for the oxygenation of a diverse range of N‐heterocyclic compounds. Scalable biocatalytic oxygenations (27 preparative examples, ca. 100 mg scale) have been develo...

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Detalles Bibliográficos
Autores principales: Pogrányi, Balázs, Mielke, Tamara, Díaz‐Rodríguez, Alba, Cartwright, Jared, Unsworth, William P., Grogan, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107140/
https://www.ncbi.nlm.nih.gov/pubmed/36453718
http://dx.doi.org/10.1002/anie.202214759