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Effect of APOE ε4 genotype on amyloid‐β, glucose metabolism, and gray matter volume in cognitively normal individuals and amnestic mild cognitive impairment

BACKGROUND AND PURPOSE: The presence of apolipoprotein E ε4 (APOE ε4) is associated with an increased risk of developing Alzheimer disease (AD). The aim of this study was to assess the effects of APOE ε4 on amyloid‐β (Aβ) pathology, glucose metabolism, and gray matter (GM) volume and their longitudi...

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Detalles Bibliográficos
Autores principales: Li, Weihua, Li, Runtian, Yan, Shaozhen, Zhao, Zhilian, Shan, Yi, Qi, Zhigang, Lu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107141/
https://www.ncbi.nlm.nih.gov/pubmed/36448771
http://dx.doi.org/10.1111/ene.15656