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Molecular interaction networks and drug development: Novel approach to drug target identification and drug repositioning

Conventional drug discovery requires identifying a protein target believed to be important for disease mechanism and screening compounds for those that beneficially alter the target's function. While this approach has been an effective one for decades, recent data suggest that its continued suc...

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Detalles Bibliográficos
Autor principal: Loscalzo, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107166/
https://www.ncbi.nlm.nih.gov/pubmed/36468661
http://dx.doi.org/10.1096/fj.202201683R