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Sodium bicarbonate reverts electrophysiologic cardiotoxicity of ropivacaine faster than lipid emulsions in a porcine model

Ropivacaine has been described as a safer local anaesthetic (LA); however, serious cardiotoxic accidents have been reported. Intravenous‐lipid‐emulsion (ILE) therapy during LA intoxication seems to act as an antidote. Sodium bicarbonate is the standard treatment for sodium channel blocker drug toxic...

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Detalles Bibliográficos
Autores principales: Zaballos, Matilde, Fernández, Ignacio, Melone, Arturo, Rodríguez, Lucía, Varela, Olalla, García, Sergio, Quintela, Oscar, Vazquez, Elena, Anadón, María José, Almendral, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107242/
https://www.ncbi.nlm.nih.gov/pubmed/36479999
http://dx.doi.org/10.1111/bcpt.13822