Mechanistic Characterisation and Engineering of Sesterviolene Synthase from Streptomyces violens

The sesterviolene synthase from Streptomyces violens was identified and represents the second known sesterterpene synthase from bacteria. Isotopic labelling experiments in conjunction with DFT calculations were performed that provided detailed insight into its complex cyclisation mechanism. Enzyme e...

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Detalles Bibliográficos
Autores principales: Gu, Binbin, Goldfuss, Bernd, Dickschat, Jeroen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107272/
https://www.ncbi.nlm.nih.gov/pubmed/36350768
http://dx.doi.org/10.1002/anie.202215688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107272/
https://www.ncbi.nlm.nih.gov/pubmed/36350768
http://dx.doi.org/10.1002/anie.202215688

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