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Mechanistic Characterisation and Engineering of Sesterviolene Synthase from Streptomyces violens
The sesterviolene synthase from Streptomyces violens was identified and represents the second known sesterterpene synthase from bacteria. Isotopic labelling experiments in conjunction with DFT calculations were performed that provided detailed insight into its complex cyclisation mechanism. Enzyme e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107272/ https://www.ncbi.nlm.nih.gov/pubmed/36350768 http://dx.doi.org/10.1002/anie.202215688 |