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Verbal fluency functional magnetic resonance imaging detects anti‐seizure effects and affective side effects of perampanel in people with focal epilepsy

Perampanel, a noncompetitive antagonist of the postsynaptic a‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic (AMPA) receptor, is effective for controlling focal to bilateral tonic–clonic seizures but is also known to increase feelings of anger. Using statistical parametric mapping–derived measures of...

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Detalles Bibliográficos
Autores principales: Xiao, Fenglai, Caciagli, Lorenzo, Wandschneider, Britta, Fleury, Marine, Binding, Lawrence, Giampiccolo, Davide, Hill, Andrea, Galovic, Marian, Foong, Jaqueline, Zhou, Dong, Sander, Josemir W., Duncan, John S., Koepp, Matthias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107311/
https://www.ncbi.nlm.nih.gov/pubmed/36524702
http://dx.doi.org/10.1111/epi.17493