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Isolation of single circulating trophoblasts from maternal circulation for noninvasive fetal copy number variant profiling
OBJECTIVE: To develop a multi‐step workflow for the isolation of circulating extravillous trophoblasts (cEVTs) by describing the key steps enabling a semi‐automated process, including a proprietary algorithm for fetal cell origin genetic confirmation and copy number variant (CNV) detection. METHODS:...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107339/ https://www.ncbi.nlm.nih.gov/pubmed/36443901 http://dx.doi.org/10.1002/pd.6275 |