Isolation of single circulating trophoblasts from maternal circulation for noninvasive fetal copy number variant profiling

OBJECTIVE: To develop a multi‐step workflow for the isolation of circulating extravillous trophoblasts (cEVTs) by describing the key steps enabling a semi‐automated process, including a proprietary algorithm for fetal cell origin genetic confirmation and copy number variant (CNV) detection. METHODS:...

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Detalles Bibliográficos
Autores principales: Doffini, Anna, Forcato, Claudio, Mangano, Chiara, Lattuada, Debora, Aversa, Roberta, Maranta, Chiara, Giovannone, Emilia D., Buson, Genny, Bolognesi, Chiara, Maiocchi, Rebecca, Dori, Martina, Jamal, Liyana, Ahmad, Raidah B., Yeo, George S. H., Yeo, Tai Wai, Saragozza, Silvia, Silipigni, Rosamaria, Serafini, Marta, Biondi, Andrea, Perego, Sofia, Vergani, Patrizia, Ferrazzi, Enrico, Ricciardi‐Castagnoli, Paola, Musci, Thomas J., Grati, Francesca Romana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107339/
https://www.ncbi.nlm.nih.gov/pubmed/36443901
http://dx.doi.org/10.1002/pd.6275

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