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NMR Investigation of Protein‐Carbohydrate Interactions: The Recognition of Glycans by Galectins Engineered with Fluorotryptophan Residues

Fluorine ((19)F) incorporation into glycan‐binding proteins (lectins) has been achieved and exploited to monitor the binding to carbohydrate ligands by nuclear magnetic resonance (NMR) spectroscopy. Galectins are a family of lectins that bind carbohydrates, generally with weak affinities, through a...

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Detalles Bibliográficos
Autores principales: Lete, Marta G., Franconetti, Antonio, Bertuzzi, Sara, Delgado, Sandra, Azkargorta, Mikel, Elortza, Félix, Millet, Oscar, Jiménez‐Osés, Gonzalo, Arda, Ana, Jiménez‐Barbero, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107428/
https://www.ncbi.nlm.nih.gov/pubmed/36343278
http://dx.doi.org/10.1002/chem.202202208