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Cyanide Binding to [FeFe]‐Hydrogenase Stabilizes the Alternative Configuration of the Proton Transfer Pathway

Hydrogenases are H(2) converting enzymes that harbor catalytic cofactors in which iron (Fe) ions are coordinated by biologically unusual carbon monoxide (CO) and cyanide (CN(−)) ligands. Extrinsic CO and CN(−), however, inhibit hydrogenases. The mechanism by which CN(−) binds to [FeFe]‐hydrogenases...

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Detalles Bibliográficos
Autores principales:	Duan, Jifu, Hemschemeier, Anja, Burr, David J., Stripp, Sven T., Hofmann, Eckhard, Happe, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107461/ https://www.ncbi.nlm.nih.gov/pubmed/36464641 http://dx.doi.org/10.1002/anie.202216903

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