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Epigenetic age acceleration is associated with oligodendrocyte proportions in MSA and control brain tissue

AIMS: Epigenetic clocks are widely applied as surrogates for biological age in different tissues and/or diseases, including several neurodegenerative diseases. Despite white matter (WM) changes often being observed in neurodegenerative diseases, no study has investigated epigenetic ageing in white m...

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Detalles Bibliográficos
Autores principales: Murthy, Megha, Shireby, Gemma, Miki, Yasuo, Viré, Emmanuelle, Lashley, Tammaryn, Warner, Thomas T., Mill, Jonathan, Bettencourt, Conceição
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107510/
https://www.ncbi.nlm.nih.gov/pubmed/36542090
http://dx.doi.org/10.1111/nan.12872