Selecting Better Biocatalysts by Complementing Recoded Bacteria

In vivo selections are powerful tools for the directed evolution of enzymes. However, the need to link enzymatic activity to cellular survival makes selections for enzymes that do not fulfill a metabolic function challenging. Here, we present an in vivo selection strategy that leverages recoded orga...

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Detalles Bibliográficos
Autores principales: Rubini, Rudy, Jansen, Suzanne C., Beekhuis, Houdijn, Rozeboom, Henriëtte J., Mayer, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107544/
https://www.ncbi.nlm.nih.gov/pubmed/36342942
http://dx.doi.org/10.1002/anie.202213942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107544/
https://www.ncbi.nlm.nih.gov/pubmed/36342942
http://dx.doi.org/10.1002/anie.202213942

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