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Bio‐Inspired Deaminative Hydroxylation of Aminoheterocycles and Electron‐Deficient Anilines
Among the tools available to chemists for drug design of bioactive compounds, the bioisosteric replacement of atoms or groups of atoms is the cornerstone of modern strategies. Despite the undeniable interest in amino‐to‐hydroxyl interchange, enzymatic deaminative hydroxylation remains unmatched. Her...
Autores principales: | Ghiazza, Clément, Wagner, Lucas, Fernández, Sergio, Leutzsch, Markus, Cornella, Josep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107619/ https://www.ncbi.nlm.nih.gov/pubmed/36479796 http://dx.doi.org/10.1002/anie.202212219 |
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