Bio‐Inspired Deaminative Hydroxylation of Aminoheterocycles and Electron‐Deficient Anilines

Among the tools available to chemists for drug design of bioactive compounds, the bioisosteric replacement of atoms or groups of atoms is the cornerstone of modern strategies. Despite the undeniable interest in amino‐to‐hydroxyl interchange, enzymatic deaminative hydroxylation remains unmatched. Her...

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Detalles Bibliográficos
Autores principales: Ghiazza, Clément, Wagner, Lucas, Fernández, Sergio, Leutzsch, Markus, Cornella, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107619/
https://www.ncbi.nlm.nih.gov/pubmed/36479796
http://dx.doi.org/10.1002/anie.202212219