Cargando…

Deaminative chlorination of aminoheterocycles

Selective modification of heteroatom-containing aromatic structures is in high demand as it permits rapid evaluation of molecular complexity in advanced intermediates. Inspired by the selectivity of deaminases in nature, herein we present a simple methodology that enables the NH(2) groups in aminohe...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghiazza, Clément, Faber, Teresa, Gómez-Palomino, Alejandro, Cornella, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755540/
https://www.ncbi.nlm.nih.gov/pubmed/34916597
http://dx.doi.org/10.1038/s41557-021-00812-0