Chiral Alcohols from Alkenes and Water: Directed Evolution of a Styrene Hydratase

Enantioselective synthesis of chiral alcohols through asymmetric addition of water across an unactivated alkene is a highly sought‐after transformation and a big challenge in catalysis. Herein we report the identification and directed evolution of a fatty acid hydratase from Marinitoga hydrogenitole...

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Detalles Bibliográficos
Autores principales: Gajdoš, Matúš, Wagner, Jendrik, Ospina, Felipe, Köhler, Antonia, Engqvist, Martin K. M., Hammer, Stephan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107627/
https://www.ncbi.nlm.nih.gov/pubmed/36511829
http://dx.doi.org/10.1002/anie.202215093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107627/
https://www.ncbi.nlm.nih.gov/pubmed/36511829
http://dx.doi.org/10.1002/anie.202215093

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