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Chiral Alcohols from Alkenes and Water: Directed Evolution of a Styrene Hydratase
Enantioselective synthesis of chiral alcohols through asymmetric addition of water across an unactivated alkene is a highly sought‐after transformation and a big challenge in catalysis. Herein we report the identification and directed evolution of a fatty acid hydratase from Marinitoga hydrogenitole...
Autores principales: | Gajdoš, Matúš, Wagner, Jendrik, Ospina, Felipe, Köhler, Antonia, Engqvist, Martin K. M., Hammer, Stephan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107627/ https://www.ncbi.nlm.nih.gov/pubmed/36511829 http://dx.doi.org/10.1002/anie.202215093 |
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