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A Widely Distributed Biosynthetic Cassette Is Responsible for Diverse Plant Side Chain Cross‐Linked Cyclopeptides

Cyclopeptide alkaloids are an abundant class of plant cyclopeptides with over 200 analogs described and bioactivities ranging from analgesic to antiviral. While these natural products have been known for decades, their biosynthetic basis remains unclear. Using a transcriptome‐mining approach, we lin...

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Detalles Bibliográficos
Autores principales: Lima, Stella T., Ampolini, Brigitte G., Underwood, Ethan B., Graf, Tyler N., Earp, Cody E., Khedi, Imani C., Pasquale, Michael A., Chekan, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107690/
https://www.ncbi.nlm.nih.gov/pubmed/36529706
http://dx.doi.org/10.1002/anie.202218082