Readily Accessible Strained Difunctionalized trans‐Cyclooctenes with Fast Click and Release Capabilities

The click reaction between a functionalized trans‐cyclooctene (TCO) and a tetrazine (Tz) is a compelling method for bioorthogonal conjugation in combination with payload releasing capabilities. However, the synthesis of difunctionalized TCOs remains challenging. As a result, these compounds are poor...

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Detalles Bibliográficos
Autores principales: Sondag, Daan, Maartense, Luuk, de Jong, Heleen, de Kleijne, Frank F. J., Bonger, Kimberly M., Löwik, Dennis W. P. M., Boltje, Thomas J., Dommerholt, Jan, White, Paul B., Blanco‐Ania, Daniel, Rutjes, Floris P. J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107714/
https://www.ncbi.nlm.nih.gov/pubmed/36478614
http://dx.doi.org/10.1002/chem.202203375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107714/
https://www.ncbi.nlm.nih.gov/pubmed/36478614
http://dx.doi.org/10.1002/chem.202203375

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