Tonic extracellular glutamate and ischaemia: glutamate antiporter system x(c) (−) regulates anoxic depolarization in hippocampus

ABSTRACT: In stroke, the sudden deprivation of oxygen to neurons triggers a profuse release of glutamate that induces anoxic depolarization (AD) and leads to rapid cell death. Importantly, the latency of the glutamate‐driven AD event largely dictates subsequent tissue damage. Although the contributi...

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Detalles Bibliográficos
Autores principales: Heit, Bradley S., Chu, Alex, Sane, Abhay, Featherstone, David E., Park, Thomas J., Larson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107724/
https://www.ncbi.nlm.nih.gov/pubmed/36321247
http://dx.doi.org/10.1113/JP283880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107724/
https://www.ncbi.nlm.nih.gov/pubmed/36321247
http://dx.doi.org/10.1113/JP283880

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