The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines

Imine reductases (IREDs) are NADPH‐dependent enzymes with significant biocatalytic potential for the synthesis of primary, secondary, and tertiary chiral amines. Their applications include the reduction of cyclic imines and the reductive amination of prochiral ketones. In this study, twenty‐nine nov...

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Detalles Bibliográficos
Autores principales: Cárdenas‐Fernández, Max, Roddan, Rebecca, Carter, Eve M., Hailes, Helen C., Ward, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107726/
https://www.ncbi.nlm.nih.gov/pubmed/37081856
http://dx.doi.org/10.1002/cctc.202201126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107726/
https://www.ncbi.nlm.nih.gov/pubmed/37081856
http://dx.doi.org/10.1002/cctc.202201126

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