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The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines
Imine reductases (IREDs) are NADPH‐dependent enzymes with significant biocatalytic potential for the synthesis of primary, secondary, and tertiary chiral amines. Their applications include the reduction of cyclic imines and the reductive amination of prochiral ketones. In this study, twenty‐nine nov...
Autores principales: | Cárdenas‐Fernández, Max, Roddan, Rebecca, Carter, Eve M., Hailes, Helen C., Ward, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107726/ https://www.ncbi.nlm.nih.gov/pubmed/37081856 http://dx.doi.org/10.1002/cctc.202201126 |
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