Synthesis of an Antimicrobial Enterobactin‐Muraymycin Conjugate for Improved Activity Against Gram‐Negative Bacteria

Overcoming increasing antibiotic resistance requires the development of novel antibacterial agents that address new targets in bacterial cells. Naturally occurring nucleoside antibiotics (such as muraymycins) inhibit the bacterial membrane protein MraY, a clinically unexploited essential enzyme in p...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohrbacher, Christian, Zscherp, Robert, Weck, Stefanie C., Klahn, Philipp, Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107792/
https://www.ncbi.nlm.nih.gov/pubmed/36222466
http://dx.doi.org/10.1002/chem.202202408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107792/
https://www.ncbi.nlm.nih.gov/pubmed/36222466
http://dx.doi.org/10.1002/chem.202202408

Ejemplares similares