Benzylic deuteration of alkylnitroaromatics via amine‐base catalysed exchange with deuterium oxide

This paper describes the deuterium‐labelling of alkylnitroaromatics by base‐catalysed exchange with deuterium oxide. As the alkyl protons alpha to the aromatic ring are the most acidic sites in the molecule, regioselective hydrogen isotope exchange at this benzylic location leads to a regiospecifica...

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Detalles Bibliográficos
Autores principales: Maddocks, Stephen, Samuri, Nurul F., Ridge, Katerina, Cunningham, Ian D., Lockley, William J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107807/
https://www.ncbi.nlm.nih.gov/pubmed/36453978
http://dx.doi.org/10.1002/jlcr.4008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107807/
https://www.ncbi.nlm.nih.gov/pubmed/36453978
http://dx.doi.org/10.1002/jlcr.4008

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