Synthesis and Biological Evaluation of C(13)/C(13′)‐Bis(desmethyl)disorazole Z

We describe the total synthesis of the macrodiolide C(13)/C(13′)‐bis(desmethyl)disorazole Z through double inter‐/intramolecular Stille cross‐coupling of a monomeric vinyl stannane/vinyl iodide precursor to form the macrocycle. The key step in the synthesis of this precursor was a stereoselective al...

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Detalles Bibliográficos
Autores principales: Bold, Christian Paul, Lucena‐Agell, Daniel, Oliva, María Ángela, Díaz, José Fernando, Altmann, Karl‐Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107878/
https://www.ncbi.nlm.nih.gov/pubmed/36281761
http://dx.doi.org/10.1002/anie.202212190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107878/
https://www.ncbi.nlm.nih.gov/pubmed/36281761
http://dx.doi.org/10.1002/anie.202212190

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