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Pharmacological inhibition of SK‐channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events

BACKGROUND: Obstructive sleep apnea (OSA) creates a complex substrate for atrial fibrillation (AF), which is refractory to many clinically available pharmacological interventions. We investigated atrial antiarrhythmogenic properties and ventricular electrophysiological safety of small‐conductance Ca...

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Detalles Bibliográficos
Autores principales: Linz, Benedikt, Hesselkilde, Eva M., Skarsfeldt, Mark A., Hertel, Julie N., Sattler, Stefan M., Yan, Yannan, Tfelt‐Hansen, Jacob, Diness, Jonas G., Bentzen, Bo H., Linz, Dominik, Jespersen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107889/
https://www.ncbi.nlm.nih.gov/pubmed/36482155
http://dx.doi.org/10.1111/jce.15769