Synthetic Zwitterionic Streptococcus pneumoniae Type 1 Oligosaccharides Carrying Labile O‐Acetyl Esters

We herein report the first total synthesis of the Streptococcus pneumoniae serotype 1 (Sp1) oligosaccharide, a unique zwitterionic capsular polysaccharide carrying labile O‐acetyl esters. The target oligosaccharides, featuring rare α‐2,4‐diamino‐2,4,6‐trideoxy galactose (AAT) and α‐galacturonic acid...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Gimeno, Ana, Lete, Marta G., Overkleeft, Herman S., van der Marel, Gijsbert A., Chiodo, Fabrizio, Jiménez‐Barbero, Jesús, Codée, Jeroen D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107948/
https://www.ncbi.nlm.nih.gov/pubmed/36350770
http://dx.doi.org/10.1002/anie.202211940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107948/
https://www.ncbi.nlm.nih.gov/pubmed/36350770
http://dx.doi.org/10.1002/anie.202211940

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