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Synthetic Zwitterionic Streptococcus pneumoniae Type 1 Oligosaccharides Carrying Labile O‐Acetyl Esters

We herein report the first total synthesis of the Streptococcus pneumoniae serotype 1 (Sp1) oligosaccharide, a unique zwitterionic capsular polysaccharide carrying labile O‐acetyl esters. The target oligosaccharides, featuring rare α‐2,4‐diamino‐2,4,6‐trideoxy galactose (AAT) and α‐galacturonic acid...

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Detalles Bibliográficos
Autores principales:	Wang, Zhen, Gimeno, Ana, Lete, Marta G., Overkleeft, Herman S., van der Marel, Gijsbert A., Chiodo, Fabrizio, Jiménez‐Barbero, Jesús, Codée, Jeroen D. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107948/ https://www.ncbi.nlm.nih.gov/pubmed/36350770 http://dx.doi.org/10.1002/anie.202211940

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