Fluorogenic Granzyme A Substrates Enable Real‐Time Imaging of Adaptive Immune Cell Activity

Cytotoxic immune cells, including T lymphocytes (CTLs) and natural killer (NK) cells, are essential components of the host response against tumors. CTLs and NK cells secrete granzyme A (GzmA) upon recognition of cancer cells; however, there are very few tools that can detect physiological levels of...

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Detalles Bibliográficos
Autores principales: Cheng, Zhiming, Thompson, Emily J, Mendive‐Tapia, Lorena, Scott, Jamie I, Benson, Sam, Kitamura, Takanori, Senan‐Salinas, Ana, Samarakoon, Youhani, Roberts, Edward W, Arias, Maykel A, Pardo, Julian, Galvez, Eva M, Vendrell, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108010/
https://www.ncbi.nlm.nih.gov/pubmed/36562327
http://dx.doi.org/10.1002/anie.202216142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108010/
https://www.ncbi.nlm.nih.gov/pubmed/36562327
http://dx.doi.org/10.1002/anie.202216142

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