The Ketosynthase Domain Controls Chain Length in Mushroom Oligocyclic Polyketide Synthases

The nonreducing iterative type I polyketide synthases (NR‐PKSs) CoPKS1 and CoPKS4 of the webcap mushroom Cortinarius odorifer share 88 % identical amino acids. CoPKS1 almost exclusively produces a tricyclic octaketide product, atrochrysone carboxylic acid, whereas CoPKS4 shows simultaneous hepta‐ an...

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Detalles Bibliográficos
Autores principales: Löhr, Nikolai A., Urban, Maximilian C., Eisen, Frederic, Platz, Lukas, Hüttel, Wolfgang, Gressler, Markus, Müller, Michael, Hoffmeister, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108026/
https://www.ncbi.nlm.nih.gov/pubmed/36507600
http://dx.doi.org/10.1002/cbic.202200649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108026/
https://www.ncbi.nlm.nih.gov/pubmed/36507600
http://dx.doi.org/10.1002/cbic.202200649

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