Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis

OBJECTIVE: This study was undertaken to identify key disease pathways driving conventional dendritic cell (cDC) alterations in systemic sclerosis (SSc). METHODS: Transcriptomic profiling was performed on peripheral blood CD1c+ cDCs (cDC2s) isolated from 12 healthy donors and 48 patients with SSc, in...

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Detalles Bibliográficos
Autores principales: Servaas, Nila H., Hiddingh, Sanne, Chouri, Eleni, Wichers, Catharina G. K., Affandi, Alsya J., Ottria, Andrea, Bekker, Cornelis P. J., Cossu, Marta, Silva‐Cardoso, Sandra C., van der Kroef, Maarten, Hinrichs, Anneline C., Carvalheiro, Tiago, Vazirpanah, Nadia, Beretta, Lorenzo, Rossato, Marzia, Bonte‐Mineur, Femke, Radstake, Timothy R. D. J., Kuiper, Jonas J. W., Boes, Marianne, Pandit, Aridaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Systemic Sclerosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108054/
https://www.ncbi.nlm.nih.gov/pubmed/36482877
http://dx.doi.org/10.1002/art.42319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108054/
https://www.ncbi.nlm.nih.gov/pubmed/36482877
http://dx.doi.org/10.1002/art.42319

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