A Triazolium‐Anchored Self‐Immolative Linker Enables Self‐Assembly‐Driven siRNA Binding and Esterase‐Induced Release

The increased importance of RNA‐based therapeutics comes with a need to develop next‐generation stimuli‐responsive systems capable of binding, transporting and releasing RNA oligomers. In this work, we describe triazolium‐based amphiphiles capable of siRNA binding and enzyme‐responsive release of th...

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Detalles Bibliográficos
Autores principales: Hollstein, Selina, Ali, Lamiaa M. A., Coste, Maëva, Vogel, Julian, Bettache, Nadir, Ulrich, Sébastien, von Delius, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108132/
https://www.ncbi.nlm.nih.gov/pubmed/36346344
http://dx.doi.org/10.1002/chem.202203311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108132/
https://www.ncbi.nlm.nih.gov/pubmed/36346344
http://dx.doi.org/10.1002/chem.202203311

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