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A Triazolium‐Anchored Self‐Immolative Linker Enables Self‐Assembly‐Driven siRNA Binding and Esterase‐Induced Release
The increased importance of RNA‐based therapeutics comes with a need to develop next‐generation stimuli‐responsive systems capable of binding, transporting and releasing RNA oligomers. In this work, we describe triazolium‐based amphiphiles capable of siRNA binding and enzyme‐responsive release of th...
Autores principales: | Hollstein, Selina, Ali, Lamiaa M. A., Coste, Maëva, Vogel, Julian, Bettache, Nadir, Ulrich, Sébastien, von Delius, Max |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108132/ https://www.ncbi.nlm.nih.gov/pubmed/36346344 http://dx.doi.org/10.1002/chem.202203311 |
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