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Blood-CNS barrier dysfunction in amyotrophic lateral sclerosis: Proposed mechanisms and clinical implications

There is strong evidence for blood-brain and blood-spinal cord barrier dysfunction at the early stages of many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Since impairment of the blood-central nervous system barrier (BCNSB) occurs during the pre-symptomatic stages of A...

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Detalles Bibliográficos
Autores principales: Steinruecke, Moritz, Lonergan, Rebecca Murphy, Selvaraj, Bhuvaneish T, Chandran, Siddharthan, Diaz-Castro, Blanca, Stavrou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108188/
https://www.ncbi.nlm.nih.gov/pubmed/36704819
http://dx.doi.org/10.1177/0271678X231153281