Combination of Two Monoclonal Anti–Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase‐4–Dependent Manner

OBJECTIVE: The appearance of anti–citrullinated protein antibodies (ACPAs) in the circulation represents a major risk factor for developing rheumatoid arthritis (RA). Patient‐derived ACPAs have been shown to induce pain and bone erosion in mice, suggesting an active role in the pathogenicity of RA....

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Akilan, Circiumaru, Alexandra, Sun, Jitong, Kisten, Yogan, Damberg, Peter, Sakuraba, Koji, Sandor, Katalin, Jarvoll, Patrik, Zhou, Tunhe, Malmström, Vivianne, Svensson, Camilla I., Hensvold, Aase, Catrina, Anca I., Klareskog, Lars, Réthi, Bence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108252/
https://www.ncbi.nlm.nih.gov/pubmed/35930718
http://dx.doi.org/10.1002/art.42320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108252/
https://www.ncbi.nlm.nih.gov/pubmed/35930718
http://dx.doi.org/10.1002/art.42320

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