Iron‐Catalysed Carbene Transfer to Isocyanides as a Platform for Heterocycle Synthesis

An iron‐catalysed carbene transfer reaction of diazo compounds to isocyanides has been developed. The resulting ketenimines are trapped in situ with various bisnucleophiles to access a range of densely functionalized heterocycles (pyrimidinones, dihydropyrazolones, 1H‐tetrazoles) in a one‐pot proces...

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Detalles Bibliográficos
Autores principales: Roose, Thomas R., Preschel, H. Daniel, Mayo Tejedor, Helena, Roozee, Jasper C., Hamlin, Trevor A., Maes, Bert U. W., Ruijter, Eelco, Orru, Romano V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108253/
https://www.ncbi.nlm.nih.gov/pubmed/36305372
http://dx.doi.org/10.1002/chem.202203074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108253/
https://www.ncbi.nlm.nih.gov/pubmed/36305372
http://dx.doi.org/10.1002/chem.202203074

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